Spearhead Calculator
Predict treatment response with XGBoost models
Matthias Unterhuber
Description
Predict individual response to spironolactone therapy in HFpEF patients using a gradient-boosting model. Input patient data to estimate treatment effect. Provides research-based predictions for clinical validation.
SPEARHEAD is a research tool designed to explore and predict individual response to spironolactone therapy in patients with heart failure with preserved ejection fraction (HFpEF). Built on a gradient-boosting (XGBoost) model, it provides individualized estimates of treatment effect for research and validation purposes. It is powered by the model presented in the following study: 10.1016/j.ebiom.2023.104795.
Disclaimer
This application is intended solely for research and scientific validation purposes.
It does not provide medical diagnosis or treatment recommendations.
Users must not rely on the results for clinical decisions and should always seek professional medical advice before making any medical or therapeutic decision.